1. S. Shurooque Kanneth, A. Thoyyiba  and Lakshmi Chakkumkumarath^*, “Substituent-regulated photophysical properties of 8a-methyl-2,3-diphenylindolizin-1(8aH)-one derivatives and their application in the detection of bilirubin in blood and urine” New J. Chem., 2025, 49, 2484.

2. Vannappilakkal Sreelaya, Vasu Drisya, Lakshmi Chakkumkumarath* “A pyrene-based fluorescent sensor for the discrimination and estimation of hydrazine and hydrogen sulfide and its application in assessing food spoilage” Journal of Hazardous Materials, 487 (2025) 137151.

3. S. Shurooque Kanneth, V. C. Saheer and Lakshmi Chakkumkumarath^* “1,4-Dihydropyridine-based FA1 site-specific fluorescent probes for the selective detection and quantification of HSA levels in biofluids” Analyst, 2024, 149, 4633 (Analyst Hot Articles 2024)

4. V. Sreelaya, S. S. Rohman, P. Parameswaran* and L. Chakkumkumarath* "An investigation of the excitation wavelength-dependent dynamic changes in the mechanism of detection of picric acid using pyrene-based donor-acceptor systems", ChemPhysChem 2024, e202400264. DOI: 10.1002/cphc.202400264.

5. Kanneth S. Shurooque, Diana Mathew, Pattiyil Parameswaran, Anjali K. Sajeev, K. N. Narayanan Unni, and Lakshmi Chakkumkumarath^* “Substituent-controlled photophysical responses in dihydropyridine derivatives and their application in the detection of volatile organic contaminants” J. Org. Chem. 2023, 88, 15007−15017.

6. Vasu Drisya, Kanneth S. Shurooque, Soumya Das, and Lakshmi Chakkumkumarath^*“Fmoc-phenylalanine-based fluorimetric and colorimetric dual-channel probes for the detection of Fe³⁺, Cu²⁺ and F^-” Journal of Photochemistry & Photobiology, A: Chemistry 442 (2023) 114796.

7. Thekke Kunhalath Jithinraj, Velluvakandi Chaluvalappil Saheer and Lakshmi Chakkumkumarath *, "Chiral 8-aminoBODIPY-based fluorescent probes with site selectivity for the quantitative detection of HSA in biological samples", Analyst, 2023, 148, 286 (Analyst Hot Articles 2023).

8. Jais Kurian, Kanneth S. Shurooque, Venkatachalam Ramkumar, Lakshmi Chakkumkumarath* and Muraleedharan Kannoth M*, “Delocalization Effects and Tunable Emission in a Class of Charged Cyclazines with Nitrogen on the Periphery”, Org. Lett. 2021, 23, 3354−3358.

9. Thekke Thattariyil Divya, Darpan Raghav, Krishnan Rathinasamy*, Lakshmi Chakkumkumarath*, “Multifunctional fluorescent leucomalachite green derivatives for chemodosimetric detection of Fe3+, specific imaging of lipid droplets and intracellular pH monitoring”, New J. Chem., 2019,43, 16349-16358.

10. R. Kalluruttimmal, D. T. Thattariyil, A. P. Parambil, A. K. Sen, L. Chakkumkumarath*, and K. M. Muraleedharan* “Electronically-tuned Triarylmethine Scaffold for Fast and Continuous Monitoring of H2S Levels in Biological Samples,” Analyst, 2019, 144, 4210–4218.

11. T. T. Divya, K. Ramshad, V. C. Saheer, and L. Chakkumkumarath*, “Self-reversible Mechanochromism and Aggregation Induced Emission in Neutral Triarylmethanes and their Application in Water Sensing,” New J. Chem., 2018, 42, 20227–20238.

12. Abhineeshbabu Thottiparambil, Indu Purushothaman, Susmita De, Pattiyil Parameswaran*, P. Shifana Beegum, P. K. Sudhadevi Antharjanam, and Lakshmi Chakkumkumarath*,“Differential reactivity of 3H-indole styrylcyanines: Intermolecular [4π + 2π] cycloaddition vs. proton - shift coupled six - electron electrocyclization”, Tetrahedron, 2018, 74, 2999-3006.

13. A. Thottiparambil, P. R. Anil Kumar and L. Chakkumkumarath*, Styrylcyanine-based ratiometric and tunable fluorescent pH sensors”, RSC Adv., 2014, 4, 56063-56067.

14. Leevy, M. W; Johnson, J. R; Lakshmi, C; Morris, J; Marquez, M; Smith, B. D."Selective recognition of bacterial membranes by zinc (II)-coordination complexes". Chem Commun, 2006, 15, 1595- 1597.

15. Hanshaw, R. G; Lakshmi, C; Lambert, T. N; Smith, B. D. "Fluorescent detection of apoptotic cells by using a zinc coordination complex with a selective affinity for membrane surfaces enriched with phosphatidylserine". Chembiochem, 2005, 6(12), 2214-2220.

16. Koulov, A. V.; Hanshaw, R. G.; Stucker, K. A.; Lakshmi, C; Smith, B. D. "Biophysical studies of a synthetic mimic of the apoptosis-detecting protein annexin V". Israel Journal of Chemistry, 2005, 45, 373-379.

17. Lakshmi, C.; Hanshaw, R. G; Smith, B. D. "Fluorescent labeled Zn-complexes as sensors for phosphatidylserine enriched surfaces", Tetrahedron, 2004, 60, 11307-11315.

18. Koulov, A. V.; Stucker, K. A.; Lakshmi, C.; Robinson, P. J.; Smith, B. D."Detection of apoptotic cells using a fluorescent sensor for membrane surfaces that contain phosphatidylserine", Cell Death Differ., 2003, 10(12), 1357-1359. Highlighted in Chem. Eng. News, 2003 October 6 issue.

19. Ranganathan, D.; Lakshmi, C. "Cystine-based cyclic oligoureas: a new class of hydrogen-bonding electroneutral anion receptors", Chem Commun, 2001, 14, 1250- 1251.

20. Karle, I. L.; Ranganathan, D.; Lakshmi, C. "Demonstration of cystine unit as a promising turn-scaffold for the design of parallel U-shaped two-helix bundle motif. Crystal structure of Cyst (Aibn)2 (n = 3, 4)", Biopolymers, 2001, 59, 301-304.

21. Ranganathan, D.; Lakshmi, C.; Haridas, V.; Gopikumar, M. "Designer cyclopeptides for self-assembled tubular structures", Pure. Appl. Chem. 2000, 72, 355-362.

22. Ranganathan, D.; Lakshmi, C.; Karle, I. L. "Hydrogen-bonded self-assembled peptide nanotubes from cystine-based macrocyclic bisureas", J. Am. Chem. Soc, 1999, 121, 6103-6107.

Bio-organic Chemistry and Physical Organic Chemistry

• Design and synthesis of luminescent organic molecules for cell imaging and analyte detection.

• Supramolecular approach for the design of new luminescent materials.

• K. M. Muraleedharan, C. Lakshmi, K. Ramshad and T. T. Divya, “A method for the selective and sensitive quantification of hydrogen sulfide (H₂S) using malachite green derivatives”, Indian Patent, 201741043637, 2017

• "Design and synthesis of Spiropyran based size tunable ionophores: Modular systems for ion transport, sensing and antimicrobial applications", Principal Investigator, Funding Agency: NIT Calicut under Faculty Research Grant Scheme (Amount: 5 Lakhs, Duration: 2010-2013).

• "Development of Pro-fluorophore Scaffolds to Probe Peptide Aggregation and Conformational Transitions" Principal Investigator, Funding Agency: Department of Science and Technology, Govt. of India (Amount: 20.7 Lakhs, Duration: 2011-2015).

• "Design, synthesis and evaluation of solid-emissive far red- near lR fluorophores" Principal Investigator, Funding Agency: Department of Science and Technology, Govt. of India (Amount: 40 Lakhs, Duration: 2017-2020).

1. T. T. Divya, L. Chakkumkumarath, “Pyrene-based solid-emissive and AIE active fluorophore with mega stokes shift for sensing water and micro-environment viscosity changes,” 30^th Kerala Science Congress held at Government Brennen College, Thalassery during 28-30^th January, 2018.

2. T. T. Divya, L. Chakkumkumarath, “Self-reversible mechanochromism and aggregation induced emission in neutral triarylmethanes and their application in water sensing,” International Conference on Materials for the Millennium, MATCON 2019 held at CUSAT during 14-16^th March, 2019.

3. C. Lakshmi, Roger G. Hanshaw and Bradley D. Smith. "Zn (II)-dipicolylamine coordination complexes as markers of apoptosis" - Abstract of papers, 228th ACS National Meeting, Philadelphia, PA, USA, August 22-26, 2004.

4. C. Lakshmi, Roger G. Hanshaw and Bradley D. Smith. "Zn (II)-dipicolylamine coordination complexes as markers of apoptosis" - Abstract of papers, 13th International Symposium on Supramolecular Chemistry, Notre Dame, Indiana, USA, July 25-30, 2004.