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Dr. K. Rajasekhara Reddy
Dr. K. Rajasekhara Reddy
Assistant Professor
Office Address:
Bioscience and Engineering, National Institute of Technology Calicut 673601, Kerala, India.
Ph.D. Biochemistry, University of Houston, Texas, United States. (2012-2017)
B.Tech Biotechnology, NIT Warangal, Telangana. ( 2007-2011).
Educational Qualifications
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Ph.D. Biochemistry, University of Houston, Texas, United States. (2012-2017)
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B.Tech Biotechnology, NIT Warangal, Telangana. ( 2007-2011).
Journals
- Maity D, Katreddy RR, Bandhu A. Molecular Cloning, Purification and Characterization of Mce1R of Mycobacterium tuberculosis. Mol Biotechnol. 2021 Mar;63(3):200-220. doi: 10.1007/s12033-020-00293-5. Epub 2021 Jan 9. PMID: 33423211.
- Thomas, R., Srivastava, S., Katreddy, R. R., Sobieski, J., and Weihua, Z. (2019) Kinase- Inactivated EGFR Is Required for the Survival of Wild-Type EGFR-Expressing Cancer Cells Treated with Tyrosine Kinase Inhibitors. International journal of molecular sciences 20.
- Katreddy, R. R., Bollu, L. R., Su, F., Xian, N., Srivastava, S., Thomas, R., Weihua, Z. (2018). Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt. Oncogenesis, 7(1), 5.
- White, M. A., Tsouko, E., Lin, C., Rajapakshe, K., Spencer, J. M., Wilkenfeld, S. R., Vakili, S. S., Pulliam, T. L., Awad, D., Nikolos, F., Katreddy, R. R., Kaipparettu, B. A., Sreekumar, A., Zhang, X., Cheung, E., Coarfa, C., and Frigo, D. E. (2018) GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling. Endocrine-related cancer 25, 453-469.
- Bollu, L. R., Katreddy, R. R., Blessing, A. M., Pham, N., Zheng, B., Wu, X., & Weihua,Z. (2015). Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation. Oncotarget, 6(33), 34992–5003.
- Bollu, L. R., Ren, J., Blessing, A. M., Katreddy, R. R., Gao, G., Xu, L. Zhang, W. (2014). Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells. Cell Cycle, 13(15), 2415–2430.
Professional Experience
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Jul 2018- Aug 2020 : Research Associate at Department of Biotechnology, NIT Warangal, India
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Dec 2020- Jul 2022 : RA-II and Sr. Research Associate at Hetero Biopharma Pvt. Ltd., Telangana, India.
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Aug 2022- On going : Assistant Professor (Grade-II) at School of Biotechnology, NIT Calicut.
Research Area
Cancer metabolism and Signaling pathways in cancer.
BT2003D: Biochemical Thermodynamics
BT3003D: Downstream Processing
BT1001D: Introduction to Life Science
BT3005D: Enzyme Kinetics and Technology
BT3030D: Metabolic Engineering